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He was born in 1539, at Sienna, and imbibed his opinions from the instruction of his uncle, who always had a high opinion of, and confidence in, the abilities of his nephew, to whom he bequeathed all his papers.

This prince was afterwards a good friend to the master, and his letter of September 7, 1539, informs us of the position of affairs with regard to the Tomb of Julius during the progress of the large painting in the Sistine:—

Besides making so many gifts to Sta. Cruz, Dom Manoel endowed it with many privileges. The priors were exempt from the jurisdiction of the bishop, and had themselves complete control over their own dependent churches. All the canons were chaplains to the king, and after the university came back to Coimbra from Lisbon in 1539 Dom João III. made the priors perpetual chancellors.

Alfonso d'Avalos, Francesco della Croce, the jurisconsult whose name has already been mentioned, and the senator Sfondrato, were doing their best to bring the physicians of the city into a more reasonable temper, and they finally succeeded in 1539; when, after having been denied admission for twelve years, Jerome Cardan became a member of the College, and a sharer in all the privileges appertaining thereto.

On the afternoon of Whitsunday, May 24, 1539, Luther preached a sermon in the court chapel of that Castle of Pleissenburg, where he had once disputed before George with Eck, and on the following afternoon he preached in one of the churches of the town, not venturing to do so in the morning on account of his weak state of health.

This building is of late, almost transition, Norman date; and is not very many years later than the transept itself. It can be seen from the cloister court that it had originally three gables. The roof is vaulted. In an inventory of goods made in 1539, printed in Gunton, there is one chapel described as the "Ostrie Chapel," which is believed to refer to this building. Sprite or the Holy Ghost."

When the fore-and-aft-trimmed sails were invented in 1539, the modern age began. This has three distinctive eras of its own. The first lasted for about a century after the time of Jacques Cartier; and its chief work was to free itself of ancient and mediaeval limitations.

Cardan's reply of March 19, 1539, is friendly too friendly indeed and the wonder is that Tartaglia's suspicions were not aroused by its almost sugary politeness. It begins with an attempt to soften down the asperities of their former correspondence, some abuse of Giovanni Colla, and an apology for the rough words of his last epistle.

He came back in 1519, invested with the powers of a Provincial Inquisitor, which he exercised till 1539, when he died and was buried in the cathedral, where a monument with an alabaster effigy marked his tomb till 1625, when it was destroyed by the Hollanders. Rodrigo Bastidas, a native of Santo Domingo, was Manso's successor.

This was in the end of the year 1539, when Buchanan had attained the age of thirty-three. His residence in the capital of the famous province of Gascony seems to have been active and happy.