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He holds that the observations in myxedema, in obesity, and psoriasis warrant the belief that the thyroid gland eliminates a material having a regulating influence upon the constitution of the panniculus adiposus and upon the nutrition of the skin in general. Of the three cases in which the result was not satisfactory, one had nephritis with severe Graves' disease, and the third psoriasis.

He says: "Of all the accidental productions met with among cattle, with the exception of wens, a certain kind of indurated tumor, chiefly situated about the head and throat, has abounded most in my practice. "The affection often commences in one of the thyroid glands, which slowly but gradually increases in size, feels firm when grasped, and evinces very little tenderness.

Accordingly it is well to remember in connection with these exercises that many movements which assist in the development of the neck muscles also serve to stimulate the activities of the thyroid gland. You cannot go through the process of training for a wrestling match without stimulating this organ to an exceptional degree.

If the patient seems to be improving on small doses of iodid, however, and the thyroid is supposed not to be very deficient, it is better not to administer thyroid extract, unless the patient is obese. This first consisted of sodium sulphate, sodium chlorid, sodium phosphate, sodium bicarbonate and potassium sulphate in water in such amounts as to stimulate the blood plasma.

The thyroid body, situated in the neck and the enlargement of which is called goitre, secretes substances which pass into the blood, and which are necessary for the growth of the body in childhood, for the development of the mind and for the nutrition of the tissues of the skin.

The thyroid is the uppermost cartilage of the larynx and the Adam's apple is the uppermost portion of the front of the larynx. But as the shields open out back of the Adam's apple, they slope upward and at the extreme back each shield has a marked upward prolongation like a horn.

Place a finger on the Adam's apple, slide it down a little way, and the slight depression there met with locates the front opening, covered with yielding membrane, between the thyroid and cricoid cartilages.

The cartilages are the epiglottis, thyroid, cricoid, arytenoid, the two small, unimportant cornicula laryngis, or cartilages of Santorini, surmounting the arytenoids, and the two cuneiform, or cartilages of Wrisberg, in the folds of mucous membrane on each side of the arytenoids. The muscles are attached to the main cartilages.

Mercury used in the treatment of syphilis is more liable, however, than syphilis to be the cause of arteriosclerosis. Although this drug, even with the arsenic injections now in vogue, is necessary for the cure of syphilis, it probably tends to raise the blood pressure by irritating the kidneys and by diminishing the thyroid secretion, both of these occurrences predisposing to arteriosclerosis.

Here enters upon the scene that organ of external and internal secretion, the prostate, the most important of the accessory sex glands in the male. Experiments with its extract upon growing tadpoles have demonstrated it to have the same differentiating effects as thyroid, but without the poisoning effects.