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The inflammation of sunburn is succeeded by the brown pigmentation that henceforth stands guard like the photographer's ruby window, protecting the deeper layers of the skin. The black skin of the negro was no longer a mystery. It is his protection against the fierce sunlight of the tropics and the injurious effect of its chemical ray.

Unlike other white men in the tropics, he was there because he liked it. His protective skin pigmentation was excellent. He had been born to the sun. One he was in ten thousand in the matter of sun-resistance. The invisible and high-velocity light waves failed to bore into him. Other white men were pervious.

He had to sit by while an extremely self-confident young Darian doctor one of his names was Korvan rather condescendingly demonstrated that the former blue pigmentation was a viral product quite unconnected with the plague, and that it had been wiped out by a very trivial epidemic of such and such. Calhoun regarded that young man with a detached interest.

It is, however, curious to consider that the factor which produces intense pigmentation of the skin and all the connective tissue in the Silky fowl has no effect on the colour of the plumage in that breed, which is a recessive white.

He envied Gloria who could hide her fatigue with careful pigmentation. In his bathroom he contemplated himself in the mirror and saw that he was unusually white half a dozen small imperfections stood out against the morning pallor of his complexion, and overnight he had grown the faint stubble of a beard the general effect, he fancied, was unprepossessing, haggard, half unwell.

By his experiments on the pigment-cells of a frog Lister has established the relation existing between these elements and innervation, which formerly had been supposititious. Doubtless a solution of the central control of pigmentation would confirm the best theory of the cause of leukoderma i.e., faulty innervation of the skin.

Minute bodies that are not capable of being absorbed, such as particles of carbon, or of pigment used in tattooing, are taken up by the phagocytes, and in course of time removed. Larger bodies, such as needles or bullets, which are not capable of being destroyed by the phagocytes, become encapsulated. The tissues of the capsule may show evidence of iron pigmentation.

We have here, I think, an example of the essential difference between mutations and somatic modifications. Absence of the gametic factor or factors for pigmentation results in albinism, and no amount of exposure to light produces pigmentation in albinos, e.g. albino Axolotls which are well known in captivity. Absence of light, on the other hand, prevents the development of pigment.

Tall and slender, or generally undersized, the muscles are soft and flabby as a woman's. The hands and feet are small and gracile typically. Viewed in profile, the lines of the body are feminine. The breasts may reach almost the size of the female's and there may be a well-marked area of pigmentation around the nipple.

Leukoderma is a pathologic process, the result of which is a deficiency in the normal pigmentation of the skin, and possibly its appendages. Its synonyms are leukopathia, vitiligo, achroma, leukasmus, and chloasma album. In India the disease is called sufaid-korh, meaning white leprosy. It differs from albinism in being an acquired deficiency of pigment, not universal and not affecting the eye.