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When the gland is acted upon, minute purple particles appear, suspended in the now colorless or almost colorless fluid; and this change appears first in the cells next the gland, and then in those next beneath, traveling down the whole length of the tentacle.
Deep in the substance of the true skin, or in the fatty tissue beneath it, are the sweat glands. Each gland consists of a single tube with a blind end, coiled in a sort of ball about 1/60 of an inch in diameter. From this coil the tube passes upwards through the dermis in a wavy course until it reaches the cuticle, which it penetrates with a number of spiral turns, at last opening on the surface.
I have observed that when it has been taken in a sore mouth it has followed down the cheek to the sub-maxillary gland, and ended in a clear case of glanders or farcy.
Moreover, the anatomical evidence of such changes taking place is at present of the flimsiest character. If these theories be true, what, it may be asked, is the agency that causes the dendrites to contract or the neuroglia cells to expand? Is there really a soul sitting aloof in the pineal gland, as Descartes held?
This is shown in the beardless face and almost hairless body of Mongols and Negroes, and especially in Nilotic tribes of Negroes with long, stork-like legs, which is a manifestation of abeyance of the interstitial gland. As she grows aged, and her sexual condition closes, woman assumes the coarser and more masculine appearance, due to the loss of functioning of this gland.
In such cases it is essential that they should receive the interstitial glands of the male goat. We have in hospital at the moment, however, a childless married woman of twenty-eight, who wishes devoutly for a female child. We found her sterile of a natural gland and inserted the gland of a female goat. Her transformation has been remarkable, and I am confident her first child will be a girl.
In the acute cases of Graves' disease the explosive conversion of latent energy into heat and motion is unexcelled by any other known normal or pathologic phenomenon. The ligation of arteries, the division of its nerve supply, or the excision of part of the gland, may reverse the foregoing picture and restore the normal condition.
There are other objects adapted to stimulate the nerves, which terminate in variety of membranes, and those especially which form the terminations of canals; thus the preparations of mercury particularly affect the salivary glands, ipecacuanha the stomach, aloe the sphincter of the anus, cantharides that of the bladder, and lastly every gland of the body appears to be indued with a kind of taste, by which it selects or forms each its peculiar fluid from the blood; and by which it is irritated into activity.
In the disease called acromegaly, which is due to a change in the pituitary gland, amongst other things are noted "melancholic tendencies, loss of memory and mental and physical torpor." A very profound effect on character and personality, exclusive of intelligence, is that of the sex glands.
From some peculiar derangement in the structure or, in other words, some deviation in the natural action of a gland destined to create a mild, innoxious fluid, a poison of the most deadly nature may be created; for example: That gland, which in its sound state secretes pure saliva, may, from being thrown into diseased action, produce a poison of the most destructive quality.
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