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At the hands of a multitude of observers it was shown that in certain well-known diseases of the spinal cord, with resulting paralysis, it is the ganglion cells themselves that are found to be destroyed. Similarly, in the case of sufferers from chronic insanities, with marked dementia, the ganglion cells of the cortex of the brain are found to have undergone degeneration.

Analogy would indicate that other sensations follow the same law, hence the probability is that all the sensations from one side of the body do not pass to the parietal cortex of the opposite side, but that, while the majority so pass, a portion go up to the cortex of the same side from which they come. Dr.

If in the interior, a sufficient amount of the cortex should be removed to allow of the tumour being scraped out, and care must be taken that no nodules of cartilage are left behind. In multiple chondromas of the hand, when the fingers are crippled and useless, exposure to the X-rays should be given a trial, and in extreme cases the question of amputation may have to be considered.

Fear and anger, respectively bound up with the activities of the adrenal medulla and cortex, we shall see, provide as good exemplars as any of this process. The response of the ductless glands to situations varies with their congenital capacity, and acquired susceptibility. Capacity is a question of internal chemistry, modifiable by injury, disease, accident, shock, exhaustion.

It was concluded from these facts that these areas were respectively the centres for the discharge of the nervous impulses running in each case to the muscles which were moved. These centres being aroused in the thought of the movement desired, which is the necessary mental preparation for the movement, they in turn stimulate the real motor centres which lie below the cortex at the second level.

The fact that neither Cortex nor Duplessis, who were very zealous and active officers, had succeeded in reaching the summit of the Sierra de Merodal, showed that the country was very closely watched by the guerillas. I reckoned out the distance upon a map. There were ten miles of open country to be crossed before reaching the hills.

Wernicke has observed that the size of the occipital lobes is in proportion to the size of the optic tracts, and that the occipital lobes are the centers of vision. Hughlings Jackson has observed that limited and general convulsions were often produced by disease in the cortex of the so-called motor convolutions.

It was but a short step to the inference that there must be other definite centres worth the seeking, and various observers set about searching for them. In 1867 a clew was gained by Eckhard, who, repeating a forgotten experiment by Haller and Zinn of the previous century, removed portions of the brain cortex of animals, with the result of producing convulsions.

*The Cerebrum.*—The cerebrum comprises about seven eighths of the entire brain, and occupies all the front, middle, back, and upper portions of the cranial cavity, spreading over and concealing, to a large extent, the parts beneath. The surface layer of the cerebrum is called the cortex. This is made up largely of cell-bodies, and has a grayish appearance.

What factor or agent or intelligence is active or directive in this molecular marriage of the atoms, science does not inquire. Only philosophy can deal with that problem. What can science see or find in the brain of man that answers to the soul? Only certain movements of matter in the brain cortex. What difference does it find between inert matter and a living organism?