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On longitudinal section of a long bone during the active stage of the disease, the marrow is seen to be replaced by a vascular young connective tissue which encroaches on the surrounding spongy bone, reducing it to the slenderest proportions; the formation of bone from the periosteum does not keep pace with the absorption and replacement going on in the interior, and the cortex may be reduced to a thin shell of imperfectly calcified bone which can be cut with a knife.
In the early stages, the marrow is transformed into a vascular connective tissue; its bone-eating functions are exaggerated, and the framework of the bone becomes rarefied, so that it bends under pressure as in osteomalacia. In course of time, however, new bone is formed in great abundance; it is at first devoid of lime salts, but later becomes calcified, so that the bones regain their rigidity.
This caseous material is surrounded by the thickened capsule which, as a result of peri-adenitis, tends to become adherent to and fused with surrounding structures, and particularly with layers of fascia and with the walls of veins. The caseated tissue often remains unchanged for long periods; it may become calcified, but more frequently it breaks down and liquefies.
There is a singular muscle shrinking and deforming disease, known as progressive muscular dystrophy, hitherto a complete and unsolved mystery. Newer studies of the pineal in this disease during life by means of the X-ray have shown it calcified, that is, buried in lime salts, which signifies put out of business. Recently thus another hint as to its function has been ferreted out.
It was like that idiot, Alan Shepard, putting an American flag on the moon; but it was from that idiot, Shepard, that, in girlhood one of her more original ideas was reinforced enough to become a calcified decision or at least a determined perpetual caprice. Now, as then, she knew that she had never had anything but herself to begin with and that this was as she liked it.
Walking from the mokotong he thought of a story that he often read to the children in Kwang Sook's kindergarten in Chongju, a place where he often worked for a few hours each week. But his mind distorted it as the benign and innocuous innocence of childhood is mutilated and the mutilation calcified by experience. Seoul Tiger gets on a plane.
In a considerable percentage of cases it is situated so far back in the jaw that there is no room for it to erupt properly, and it produces inflammatory disturbances and painful pressure upon the nerves of the face and the jaw. Even when it does appear it is often imperfectly developed, has fewer cusps and fewer roots than the other molars, is imperfectly covered with enamel and badly calcified.
The ossifying zone is increased in depth; the marrow is abnormally vascular; and the new bone that is formed is imperfectly calcified. [Illustration: FIG.
The osteo-sarcoma is characterised by the formation in the tumour of bone, the medullary spaces being occupied by sarcomatous cells in place of marrow. The osteoid sarcoma is characterised by the formation of a tissue resembling bone but deficient in lime salts, and the petrifying sarcoma by the formation of calcified areas in the stroma.
These shapes clustered most thickly around an immense calcified mound. They were what were left of the battling Hordes, and the mound was what had been the Metal Monster. Somewhere there were the ashes of Norhala, sealed by fire in the urn of the Metal Emperor!
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