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The second type is met with in relation to epithelioma occurring in a sinus, the sequel of suppurative osteomyelitis, compound fracture, or tuberculous disease. The patient has usually had a discharging sinus for a great number of years: we have known it to last as many as fifty.

Smyly of Dublin reported a case of suppurative disease of the temporal bone, in which the hair changed from a mouse-color to a reddish-brown; and Squire records a congenital case in a deaf mute, in whom the hair on the left side was in light patches of true auburn and dark patches of dark brown like a tortoise-shell cap; on the other side the hair was a dark brown.

In its growth, a sarcoma compresses and destroys neighbouring parts, surrounds vessels and nerves, and may lead to destruction of the skin, either by invading it, or more commonly by causing sloughing from pressure. Inflammatory and suppurative changes may take place as a result of pyogenic infection following upon sloughing of the overlying skin or upon an exploratory incision.

#Clinical Features of an Acute Circumscribed Abscess.# In the initial stages the usual symptoms of inflammation are present. Increased elevation of temperature, with or without a rigor, progressive leucocytosis, and sweating, mark the transition between inflammation and suppuration. An increasing leucocytosis is evidence that a suppurative process is spreading.

Superficial glands, when inflamed and suppurating, become enlarged, tender, fixed, and matted to one another. In the glands of the groin the suppurative process is often remarkably sluggish; purulent foci form in the interior of individual glands, and some time may elapse before the pus erupts through their respective capsules.

In exceptional cases, blisters form over the seat of the effusion, or the skin may even slough, and the clinical features may therefore come to simulate closely those of an acute suppurative condition. When the skin sloughs, an ulcer is formed with altered blood-clot in its floor like that seen in scurvy, and there is a remarkable absence of any attempt at healing.

#Diseases caused by the Staphylococcus Aureus.# As the majority of pyogenic diseases are due to infection with the staphylococcus aureus, these will be described first. #Acute osteomyelitis# is a suppurative process beginning in the marrow and tending to spread to the periosteum. The disease is common in children, but is rare after the skeleton has attained maturity.

If this is impossible, poulticing the feet or standing the animal in moist clay will help in relieving the soreness. Excessive cutting away of the horny sole is contra-indicated. Suppurative corns should be given proper drainage and treatment. LAMINITIS, "FOUNDER." This is an inflammation of the sensitive or vascular stricture of the foot. The inflammation may be acute, subacute or chronic.

Where normal resistance to infection obtains, the subject usually suffers no suppurative disturbance when the surface structures are not broken; and daily applications of the antiseptic lotion above referred to stimulates complete resolution. This may be expected in from four to ten days depending upon the extent of the injury.

Pus fistula is the characteristic lesion present, and it is the result of a suppurative inflammation of the tissues in the region. The abscess cavity or cavities are usually deep, and may involve the ligaments and vertebrae. Bruises or contusions are the most common causes. The prominence of these regions predisposes them to injury in the stable, or when rolling on rough or stony ground.