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On the other hand there are others whose hypertrophied conscience works in one of two directions. If they are zealots, convinced of the righteousness of their own decisions and conclusions, their conscience spurs them on to reforming the world.

Next I perceive hypertrophied in myself and many sympathetic human beings a passion that many animals certainly possess, the beautiful and fearless cousin of fear, Curiosity, that seeks keenly for knowing and feeling. Apart from appetites and bodily desires and blind impulses, I want most urgently to know and feel, for the sake of knowing and feeling.

One of his faculties, his memory, has indeed been hypertrophied by being unduly exercised, and his capacity for receiving information is in consequence unhealthily great; but because he lacks, in this case or in that, the sense which might enable him to digest the information received and convert it into knowledge, the food with which he has been crammed speedily passes through him, undigested and unassimilated, and the hours which he has spent in acquiring information will have done as little for his progress in the given subject as for the general growth of his mind.

On the left hand the thumb and middle fingers were hypertrophied and the index finger was as long as the middle one of the right hand. The middle finger had a lateral curvature outward, due to a displacement of the extensor tendon. This affection resembled acromegaly.

Cooper describes a woman with an enormous development of the clitoris, an imperforate uterus, and absence of vagina; at first sight of the parts they appeared to be those of a man. In 1859 Hugier succeeded in restoring a vagina to a young girl of twenty who had an hypertrophied clitoris and no signs of a vagina.