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But withal, though he must have been well aware of John Hunter's advice to Jenner on vaccination, "Don't think, make some observations," his training in the indirect reasoning and deductions of the clinician prevented him from going right on to a direct experimental test of his theories. This Brown-Séquard proceeded to do.

Brown-Séquard discovered, and which I have frequently corroborated, that many poisons are retarded in their action by placing the animal affected in a warm atmosphere. It is possible to drink with safety in England quantities of wine which here would be disagreeable in their first effect and perilous in their ultimate results.

Not less remarkable than these results are the facts, which I with others of my audience have had the opportunity of observing, as shown by M. Brown-Sequard, of the artificial production of epilepsy in animals by injuring the spinal cord, and the induction of the paroxysm by pinching a certain portion of the skin.

Of this latter fact thirteen instances were carefully recorded, and a greater number were seen; yet Brown-Sequard speaks of such cases as one of the rarer forms of inheritance.

It is not, therefore, simply the power of performing an action which is inherited, but the power of performing a whole series of actions, in a certain order. "In most of the cases of inheritance recorded by Brown-Sequard only one of the two parents had been operated upon and was affected.

Accoucheurs cause their patients to assume what is called the knee-chest position, a prone one, for the purpose of restoring the uterus to something near a natural position. Brown-Sequard recommends, in myelitis, or spinal congestion, drawing away the blood from the spine by placing the patient on his abdomen or side, with hands and feet somewhat hanging down.

Brown-Séquard added to the concept of internal secretions, fathered by Claude Bernard, the idea of a correlation, a mutual influencing of them and of the different organs of the body through them.

It renders them nervous and shaky, gives rise to palpitation, and is a factor in the production of the irritable or so-called "trotting-heart" and tends to impair the appetite and digestion." London Lancet. "I never smoke because I have seen the most efficient proofs of the injurious effects of tobacco on the nervous system." Dr. Brown-Sequard, the eminent French physiologist.

Having lost enough blood to soak through the carpet and stain the very floor, unconscious, and hovering between life and death, Sumner was carried to a sofa, thence to his hotel. From that time on the scholar endured a living death. He was carried to Paris, where Dr. Brown-Sequard tried "the fire cure" upon the spine. But for years his desk was vacant.

We are not privileged to be discursive in a little book which seeks to hit the nail on the head in every paragraph, drive it home in every page, and clinch it in every chapter, and there would be no excuse, therefore, for sketching, even in brief outline, the history of the various attempts that have been made, from Brown-Sequard, with his Elixir, to Metchnikoff, with his benevolent bacteria of the intestinal tract, to extract from Life its secret of human longevity.