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The more he became interested in special questions of disease, such as the nature of fever or fevers, the more keenly he felt the need for that fundamental knowledge of structure which just at the beginning of the century had been illuminated by the brief and glorious career of Bichat, who died when he was only one-and-thirty, but, like another Alexander, left a realm large enough for many heirs.

An example not so complete in itself, but even more fertile in consequences, having been the starting-point of the really scientific study of physiology, is the affiliation, commenced by Bichat, and carried on by subsequent biologists, of the properties of the bodily organs, to the elementary properties of the tissues into which they are anatomically decomposed.

The second new method of studying the human structure, beginning with the labors of Scarpa, Burns, and Colles, grew up principally during the first third of this century. It does not deal with organs, as did the earlier anatomists, nor with tissues, after the manner of Bichat.

And is it to be looked at as a mere accidental coincidence, that while Napoleon was modernizing the political world, Bichat was revolutionizing the science of life and the art that is based upon it; that while the young general was scaling the Alps, the young surgeon was climbing the steeper summits of unexplored nature; that the same year read the announcement of those admirable "Researches on Life and Death," and the bulletins of the battle of Marengo?

M. Picavet's laborious researches into the activities of this school of thinkers has helped us to understand the transition from the age of Condorcet to the age of Comte. M. Picavet has grouped around them, along with many obscurer names, the great scientific men of the time, like Laplace, Bichat, Lamarck, as all in the direct line of eighteenth century thought.

It was now for the first time that a true general anatomy became possible. As early as 1816 Treviranus had attempted to resolve the tissues, of which Bichat had admitted no less than twenty-one, into their simple microscopic elements. How could such an attempt succeed, Henle well asks, at a time when the most extensively diffused of all the tissues, the areolar, was not at all understood?

There are some to whom living protoplasm is a substance, even such as Harvey conceived the blood to be, "summa cum providentia et intellectu in finem certum agens, quasi ratiocinio quodam;" and who look with as little favour as Bichat did, upon any attempt to apply the principles and the methods of physics and chemistry to the investigation of the vital processes of growth, metabolism, and contractility.

Animal likenesses, so curiously traced by physiologists in human faces, came out in gestures and behavior. A book lay open for a Bichat if he had repaired thither fasting and collected. The master of the house, knowing his condition, did not dare stir, but encouraged his guests' extravangances with a fixed grimacing smile, meant to be hospitable and appropriate.

All that method could do had been accomplished by Bichat and his followers. It was for the optician to take the next step. The future of anatomy and physiology, as an enthusiastic micrologist of the time said, was in the hands of Messrs. Schieck and Pistor, famous opticians of Berlin. In those earlier days of which I am speaking, all the points of minute anatomy were involved in obscurity.

The gardens of the hospital are adorned by a bust of the great anatomist, Bichat, whose birth-place, like that of Homer, is disputed. Bourg-en-Bresse disputes the honour with Lons-le-Saunier, and Bourg possesses the splendid monument to Bichat's memory by David d'Angers.