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He repaired to his dwelling, armed himself at all points, mounted his favorite warhorse, and, issuing from the city by the gate of Elvira, was never seen or heard of more.* * Conde, part 4. The capitulation for the surrender of Granada was signed on the 25th of November, 1481, and produced a sudden cessation of those hostilities which had raged for so many years.

His brother Clarence was successfully executed for treason in February, 1478, and Richard, without a moment's hesitation, came to the front and inherited the estates. Richard had a stormy time of it up to 1481, when he was made "protector and defender of the realm" early in May. He then proceeded with a few neglected executions.

Giovan Simone, another brother, born in 1479, led a vagabond life until he joined Buonarroto in a cloth business that was bought for them by Michael Angelo. Sigismondo, born in 1481, was a soldier.

Shortly afterwards, in the year 1477, he made a voyage to the north of Europe, navigating one hundred leagues beyond Thule, when he reached an island as large as England, generally supposed to have been Iceland. In vain he had applied to Don John the Second, who ascended the throne of Portugal in 1481.

Before Mohammed died in 1481 the Osmanli Turco-Grecian nation may be said to have come into its own. It was lord de facto et de jure belli of the eastern or Greek Empire, that is of all territories and seas grouped geographically round Constantinople as a centre, with only a few exceptions unredeemed, of which the most notable were the islands of Cyprus, Rhodes, and Krete, still in Latin hands.

Known as "the Conciliator," from his attempt to reconcile the diverse views on philosophy and medicine, he had an extraordinary reputation as a practitioner and author, the persistence of which is well illustrated by the fact that eight of the one hundred and eighty-two medical books printed before 1481 were from his pen. He seems to have taught medicine in Paris, Bologna and Padua.

In 1481, Don Juan, having killed an officer of the king of Naples, was compelled to leave Rome, and escaped to Como with his wife and his son; but having left that city to seek his fortune, he died while traveling with Christopher Columbus in the year 1493. Marco Antonio became a noted poet of the school of Martial, and was secretary to Cardinal Pompeo Colonna.

In this way he obtained the printed Missal of 1481 and a number of Latin MSS. from the College of Würzburg, and other valuable books from monasteries near Mainz and Eberbach in the Duchy of Baden. It appears by Mr. Macray's Annals that his gifts to the University between 1635 and 1640 amounted to about thirteen hundred volumes, in more than twenty languages.

The library, a fine room panelled with mahogany, contains many treasures, notably three Caxtons The History of Reynard the Fox, 1481; The Chronicles of England, 1482; and The Golden Legend, 1493: the first and second folios of Shakespeare: and many examples one printed on vellum of Froissart's Chronicles. There is also a fifteenth-century manuscript of Gower's Confessio Amantis.

In 1481, Lodovico had nominated his favourite Pavian master, Amadeo, the architect of the Certosa, as Capomaestro in succession to Guiniforte Solari; but the Councillors of the Fabric declined to accept his suggestion, and sent to Strasburg for a German architect, John Nexemperger of Graz, who held the office for some years, but effected little, and was finally dismissed in 1486.