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Hippocrates brought it into repute; whatever he established, Chrysippus overthrew; after that, Erasistratus, Aristotle's grandson, overthrew what Chrysippus had written; after these, the Empirics started up, who took a quite contrary way to the ancients in the management of this art; when the credit of these began a little to decay, Herophilus set another sort of practice on foot, which Asclepiades in turn stood up against, and overthrew; then, in their turn, the opinions first of Themiso, and then of Musa, and after that those of Vectius Valens, a physician famous through the intelligence he had with Messalina, came in vogue; the empire of physic in Nero's time was established in Thessalus, who abolished and condemned all that had been held till his time; this man's doctrine was refuted by Crinas of Marseilles, who first brought all medicinal operations under the Ephemerides and motions of the stars, and reduced eating, sleeping, and drinking to hours that were most pleasing to Mercury and the moon; his authority was soon after supplanted by Charinus, a physician of the same city of Marseilles, a man who not only controverted all the ancient methods of physic, but moreover the usage of hot baths, that had been generally and for so many ages in common use; he made men bathe in cold water, even in winter, and plunged his sick patients in the natural waters of streams.