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Positive assurance, either one way or the other, is, of course, impossible, simply for the reason that the disease was not recognized until such a short time ago that no statistics of any real value for comparison are available; and, secondly, because even to-day, on account of its insidious character and the astonishing variety of its forms, and degrees of mildness and virulence, a considerable percentage of cases are yet unrecognized and unreported.

I doubt not but I shall hear many objections against the use of these troops, and that upon this question, virulence and ridicule will be equally employed.

Malarial manifestations occur all over South Africa, but in progressive degrees of virulence with the advance to warmer latitudes, and with the descent from the high table-lands to the coast levels. On the Transvaal high veldt, for example, a mild form is developed which, in midsummer, to a small extent, affects and kills sheep. It is called blaauwtong, and does not affect horses.

By his studies in the culture of bacteria of attenuated virulence he extended widely the practise of inoculation with a milder form of various diseases, with a view to producing immunity. The following papers present some of the most important of his contributions, and exemplify his extraordinary powers of lucid exposition and argument.

The cordiality between England and France was perhaps insecure, but it was cemented by their common interest in maintaining the independence of Portugal, and that, again, offered good prospects to the trading interest of England. But, at home, Clarendon found his influence threatened by increasing virulence of intrigue, and by new scandals and dissensions at Court.

The multitude enjoyed its sharp, short, stinging paragraphs; its vim and vehemence. At length its columns were turned against Major Selover with unrestrained virulence. He had no equal means of reply or defence at his command, but he had at last uttered threats of personal nature, and published King as a liar, a swindler and a coward. To all this Mr.

That vaccination could abate the virulence of, or preserve from, the smallpox, was quite incredible; none but a cheat and a quack could assert it: but that the introduction of the vaccine matter into the human frame could endow men with the qualities of a cow, was quite probable.

"He exclaimed with virulence against Uncles and Aunts; Accused the laws of England for allowing them to Possess their Estates when wanted by their Nephews or Neices, and wished HE were in the House of Commons, that he might reform the Legislature, and rectify all its abuses." "Oh! the sweet Man! What a spirit he has!" said I.

To seek to lessen the virulence by rational means would be to establish, upon an experimental basis, the hope of preparing from an active virus, easily cultivated either in the human or animal body, a vaccine-virus of restrained development capable of preventing the fatal effects of the former.

Out of every hundred persons attacked, five did not recover; and whether the virulence of the distemper increased, or the summer heats rendered its victims more easily assailable, certain it is they were carried off far more expeditiously than before. Doctor Hodges was unremitting in his attentions, but his zeal and anxiety availed nothing.