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#Clinical Examination of an Ulcer.# In examining any ulcer, we observe Its base or floor, noting the presence or absence of granulations, their disposition, size, colour, vascularity, and whether they are depressed or elevated in relation to the surrounding parts. The discharge as to quantity, consistence, colour, composition, and odour.

An isolated gumma forms a firm elastic swelling, shading off into the surroundings. If the overlying skin is destroyed and septic infection superadded, such an isolated area of bone is apt to die and furnish a sequestrum; the separation of the dead bone is extremely slow, partly from the want of vascularity in the sclerosed bone round about, and partly from the density of the sequestrum.

The owner then yielded to all our wishes, and he was destroyed with prussic acid. No morbid appearance presented itself in the brain; but, on the inner plate of the right parietal bone, near the sagittal suture, were two projections, one-sixth of an inch in length, and armed with numerous minute spicula. There was no peculiar inflammation or vascularity of any other part of the brain.

I never knew a single mistake about this. Much has been said of the profuse discharge of saliva from the mouth of the rabid dog. It is an undoubted fact that, in this disease, all the glands concerned in the secretion of saliva, become increased in bulk and vascularity.

Where light air is circulated instead of heavy blood, great vascularity serves only to make existence more ethereal. Plethora probably takes the insect nearer to the skies, instead of dragging it towards the dust.

Wounds of certain parts of the body heal more quickly than others: those of the scalp, face, and neck, for example, heal more quickly than those over the buttock or sacrum, probably because of their greater vascularity.

Proliferative changes in the synovial membrane are attended with increased vascularity and thickening of the membrane and an enlargement of its villi and fringes.

As he gained power, he increased the voluntary resistance which he made to the operator, and thus, at the same time, the amount of his own muscular exertion. It is claimed that volition is thus called forth to neglected parts, and their innervation and vascularity increased; and that so at length the normal fulness of life and function is restored.

Where the inflammation becomes infective, surgical interference is necessary. The prompt evacuation of pus, with adequate provision for wound discharge, should be attended to before extensive destruction of tissue takes place. Resolution is prompt as a rule in such cases because of the vascularity of the structures and the ease with which proper drainage may be effected.

In this disease the reflexes are increased, the discharge of energy is greatly facilitated, and metabolism is at a maximum. The same phenomena occur also after the administration of thyroid extract in large doses to normal subjects. In the course of sexual activities there is an increased action of the thyroid, which is indicated by an increase in its size and vascularity.