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Variolae et morbilli arise from moist matter confined in the body and turbid, like turbid blood. Hence the disease occurs most commonly in boys and in those who are careless about cleanliness and neglect venesection.

10th: The spots on the arms have disappeared, but there are three visible in the face. 11th: Two spots on the face are gone; the other barely perceptible. 13th: The pustule delineated in the second plate in the Treatise on the Variolae Vaccinae is a correct representation of that on the child's arm as it appears at this time. 14th: Two fresh spots appear on the face.

It does not appear that he availed himself of the information which he says, he obtained from his slave, for such I suppose he was. In his appendix to "Variolae Triumphatae," he says, "There has been a wonderful practice lately used in several parts of the world, which indeed is not yet become common in our nation.

Although it has not been in my power to extend the inquiry into the causes and effects of the variolae vaccinae much beyond its original limits, yet, perceiving that it is beginning to excite a general spirit of investigation, I think it of importance, without delay, to communicate such facts as have since occurred, and to point out the fallacious sources from whence a disease imitative of the true variolae vaccinae might arise, with the view of preventing those who may inoculate from producing a spurious disease; and, further, to enforce the precaution suggested in the former treatise on the subject, of subduing the inoculated pustule as soon as it has sufficiently produced its influence on the constitution.

It does not appear that he availed himself of the information which he says, he obtained from his slave, for such I suppose he was. In his appendix to "Variolae Triumphatae," he says, "There has been a wonderful practice lately used in several parts of the world, which indeed is not yet become common in our nation.

For further information on this subject see the first Treatise on the Var. Vac., Dr. In further corroboration of this declaration many facts have been communicated to me by various correspondents. I shall select one of them. "DEAR SIR: "Society at large must, I think, feel much indebted to you for your Inquiries and Observations on the Nature and Effects of the Variolae Vaccinae, etc., etc.

For an exemplification of what is here advanced relative to the nature of the infection when received directly from the horse see Inquiry into the Causes and Effects of the Variolae Vaccinae, pp. 27, 28, 29, 30, and p. 35; and by way of further example, I beg leave to subjoin the following intelligence received from Mr.

Attention is directed to the not infrequent ulcers of the eyes, which occur in variolae and may destroy the sight; also to ulcerations of the nose, throat, oesophagus, lungs and intestines, the latter of which often produce a dangerous diarrhoea. When variolae occurs in boys, it is recommended to tie the hands of the patient to prevent scratching. Similiter pannus tinctus de grano."

Diseases universal but not infectious. Diseases infectious but not universal like noli me tangere. Diseases neither infectious nor universal. Gilbert classifies variolae et morbilli among the universal and infectious diseases, and in the species apostemata. To this latter species belong also ignis Persicus, carbunculus and antrax.

It is the result of a disposition of the blood resembling putrescence, in which there occurs an external ebullition in the efforts of nature to purify the interior of the body and to expel to the surface the virulent material within. Accordingly the common people declare that persons who have suffered from variolae et morbilli never acquire leprosy.