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Dickinson mentions that he has had patients in his own practice who drank their own urine. Mackenzie also quotes Trousseau's history of a man who drank a liter of strong French brandy in two hours, and habitually drank the same quantity daily.
But from all I heard, I judge that there must be some degree of predisposition toward it in the person to be contaminated. I believe I have Dr. Trousseau's leave to say that the contact of a wounded or abraded surface with the matter of a leprous sore will convey the disease; this is, of course, inoculation; and he seemed to think no other method of contamination probable.
Of this heightened irritability of the nervous system, to which the name "spasmophilia" has been given in America and on the Continent, the most striking symptom is a liability alike to tetany or carpo-pedal spasm, to generalised convulsions, and to laryngismus stridulus. In addition, in most cases it is generally possible to demonstrate the presence of Chvostek's sign and of Trousseau's sign.
Chvostek's sign consists in a visible twitch of the facial musculature, especially of the orbicularis palpebrarum or of the orbicularis oris, in response to a gentle tap administered over the facial nerve in front of the ear. Trousseau's sign is the production of tetany by applying firm and prolonged pressure to the brachial nerve in the upper arm.
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