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Until finally there developed, for everyday use, a complete check and drive nerve machinery for every organ, to be used according to the exigencies of the moment, with the thyroid as the primary stimulant and controller of the drive system and the adrenal as the primary dictator over the check system.
Sporadic cretinism, or congenital myzedema, is characterized by a congenital absence of the thyroid, diminutiveness of size, thickness of neck, shortness of arms and legs, prominence of the abdomen, large size of the face, thickness of the lips, large and protruding tongue, and imbecility or idiocy. It is popularly believed that coitus during intoxication is the cause of this condition.
He obtained it as a white, finely crystalline, odorless and tasteless substance, heat stable, and analyzable. The free form separates as a sheaf of fine needles. Kendall at first called it the a-iodine compound, then named it thyroxin. There are other internal secretions of the thyroid, with a function of their own, that have no iodine. But they are secondary, and obscure.
On the other hand, thyroid extracts will intensify the action of the autonomic or drive system, so that the amount and acidity of the digestive juice is increased. The stomach cell may, therefore, be regarded as a test-reagent for the different internal secretions, as they affect the check and drive systems. These constitute an automatic device for regulating the activities of every organ.
When there is not enough of the thyroid secretion in the blood, the tissue between the cells in the brain become clogged and thickened, so that a gross barrier to the passage of the nerve impulses is created. We have here an illustration of internal secretion lack actually producing gross changes in the brain.
Recently, Leichtenstein, observing in a case of myxedema treated with the thyroid gland that the subcutaneous fat disappeared with the continuance of the treatment, was led to adopt this treatment for obesity itself and reports striking results.
But the action of thyroid could really be simulated only by some substance that could be introduced into the best possible of gasoline mixtures, to increase its combustibility by a hundred per cent or more. For that is what thyroid will do to our food. Nor has it only this destructive or combustion side.
She had become very slow in speech and gait, sensitive to cold, and languid and depressed in spirit to the point of inability to go about alone. Murray, employing the glycerin extract of the thyroid gland of a freshly killed sheep, injected twenty-four drops hypodermically, twice a week.
The factor of zeal or enthusiasm points to the thyroid. Markedly enthusiastic types are thyroid dominant types. Vigor as a third factor, the ability to stand stress and strain of continued effort is dependent upon good adrenal and interstitial cell function.
Endocrine inferiority is indeed the most frequent organic inferiority. And we may explain a number of mental types upon that basis. Thus the inferior gonado-centric, who has something wrong with his reproductive organs, will evolve in one of two directions. If his adrenal and thyroid are of poor quality, he will become the secluded introvert, shut off from the interests of normal life.
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