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Unless I have been misinformed, he has, for a considerable time, experienced persistent headache of a kephalalgic or true cerebral type, and has now advanced to the succeeding stage of taciturnity and depression, not* unaccompanied with isolation, and probably constipation: but as yet without hallucination, though possibly, and, as my experience of the great majority of these cases would induce me to say, probably he is not undisturbed by one or more of those latent, and, at first, trifling aberrations, either of the intelligence or the senses, which in their preliminary stages escape the observation of all but the expert nosologist."

Juncker also seems to have referred to this symptom: having divided tremor into active and passive, he says of the latter, “ad affectus semiparalyticos pertinent; de qualibus hic agimus, quique tremores paralytoidei vocantur.” Tremor has been adopted, as a genus, by almost every nosologist; but always unmarked, in their several definitions, by such characters as would embrace this disease.

Having made the necessary inquiries respecting these two affections, Tremor coactum of Sylvius de la Boë and of Sauvages, and Scelotyrbe festinans of the latter nosologist, which appear to be characteristic symptoms of this disease, it becomes necessary, in the next place, to endeavour to distinguish this disease from others which may bear a resemblance to it in some particular respects.