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In inoperable cases it may be possible to relieve pain by excising a portion of the nerve above the tumour, or, when this is impracticable, by resecting the posterior nerve roots and their ganglia within the vertebral canal. Diffuse or Generalised Neuro-Fibromatosis Recklinghausen's Disease.
Symmetrical bossing of the skull was present in the case shown in Figs. 136 and 137, and there were also scattered patches of brown pigmentation of the skin of the face, neck, and trunk, similar to those met with in generalised neuro-fibromatosis. Apart from fracture, the disease is recognised by the thickening and usually also by the curving of the shafts of the long bones.
Fibroid tumours of the uterus are described with myoma. Diffuse fibroma or Fibromatosis, analogous to lipomatosis, is met with in the connective tissue of the skin and sheaths of nerves, and constitutes one form of neuro-fibromatosis; a similar change is also met with in the stomach and colon. #Myxoma.# A myxoma is composed of tissue of a soft gelatinous, semifluid consistence.
Neuro-fibromatosis is frequently accompanied by pigmentation of the skin in the form of brown spots or patches scattered over the trunk. The disease is often stationary for long periods. In progressive cases the patient becomes exhausted, and usually dies of some intercurrent affection, particularly phthisis.
The best known of these are the systematic forms of fibromatosis met with in the central nervous system and in the peripheral nerves neuro-fibromatosis; in the submucous coat of the stomach gastric fibromatosis; and in the colon intestinal fibromatosis. These conditions will be described with the tissues and organs in which they occur.
The multiple, soft fibroma known as molluscum fibrosum, which depends upon a neuro-fibromatosis of the cutaneous nerves, is described with the tumours of nerves. The "painful subcutaneous nodule" is a solitary fibroma related to one of the cutaneous nerves. The hard fibroma known as keloid is described with the affections of scars.
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