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Lethodyne is poison to phlegmatic patients, who have not active power enough to wake up from it unhurt; it is relatively harmless to the vivid and impassioned, who can be put asleep by it, indeed, for a few hours more or less, but are alive enough to live on through the coma and reassert their vitality after it." I recognised as he spoke that this explanation was correct.

She drew a profile hastily. "Just that," and she showed it me. 'Twas a face like Robespierre's, grown harder and older and lined with observation. I recognised that it was in fact the essence of Sebastian. Next day, as it turned out, the Professor himself insisted upon testing lethodyne in his own person. All Nat's strove to dissuade him. "Your life is so precious, sir the advancement of science!"

It was no good; the rabbits all died with great unanimity, until the dose was so diminished that it did not send them off to sleep at all. There was no middle course, apparently, to the rabbit kind, lethodyne was either fatal or else inoperative. So it proved to sheep. The new drug killed, or did nothing.

"She WILL live to marry him," I answered, with confidence like her own, "if YOU say she can stand it." "The lethodyne oh, yes; THAT'S all right. But the operation itself is so extremely dangerous; though Dr. Sebastian says he has called in the best surgeon in London for all such cases. They are rare, he tells me and Nielsen has performed on six, three of them successfully."

"Very vivid fancy. Twitches her hands the right way. Quick pulse, rapid perceptions, no meaningless unrest, but deep vitality. I don't doubt she'll stand it." We explained to Number Fourteen the gravity of the case, and also the tentative character of the operation under lethodyne. At first, she shrank from taking it. "No, no!" she said; "let me die quietly."

I have told him already he has just the proper temperament to stand the drug. Such people are rare: HE is one of them." We administered the dose, trembling. Sebastian took it like a man, and dropped off instantly, for lethodyne is at least as instantaneous in its operation as nitrous oxide. He lay long asleep. Hilda and I watched him.

I have lost interest in it. Impracticable! It is not fitted for the human species." "Why so? Number Fourteen proves " He interrupted me with an impatient wave of his hand; then he rose and paced up and down the room testily. After a pause, he spoke again. "The weak point of lethodyne is this: nobody can be trusted to say WHEN it may be used except Nurse Wade, which is NOT science."

A royal road through disease, with no trouble to the doctor and no pain to the patient! Lethodyne held the field. We were all of us, for the moment, intoxicated with lethodyne. Sebastian's observations on the new agent occupied several months. He had begun with the raccoon; he went on, of course, with those poor scapegoats of physiology, domestic rabbits.

He was so full of the subject, however, and so utterly carried away by his scientific ardour, that I regret to say he gave a strong dose of lethodyne at once to each of the matron's petted and pampered Persian cats, which lounged about her room and were the delight of the convalescents.

A name being wanted for it, he christened it "lethodyne." It was the best pain-luller yet invented. For the next few weeks, at Nat's, we heard of nothing but lethodyne. Patients recovered and patients died; but their deaths or recoveries were as dross to lethodyne, an anaesthetic that might revolutionise surgery, and even medicine!