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Boyer successfully removed two breasts at an interval of twenty-six days between the two operations. The mass excised was one-third of the total body-weight. Hamilton reports a case of hypertrophied glands in a woman of thirty-two, which, within the short space of a year, reached the combined weight of 52 pounds. They were successfully excised.

Immediately below the corbel, and well detached from the squadrons of attendant saints, Christ rises from His throne. His face is turned in the direction of the damned, His right hand is lifted as though loaded with thunderbolts for their annihilation. He is a ponderous young athlete; rather say a mass of hypertrophied muscles, with the features of a vulgarised Apollo.

On visual examination of the subject at rest, one may note the hypertrophied condition of the affected tendons. Their transverse diameter is usually perceptibly increased and in many cases, there is an increase in the antero-posterior diameter. The latter condition causes a bulging of the tendon that is so noticeable, because of the convexity thus formed, it is commonly known as "bowed tendon."

Whether the muscles are massive or sparse, atrophied or hypertrophied, soft or hard, easily fatigable or not, bespeak conditions in the glandular chain. In short, we must regard the individual as an immensely complicated pattern of designs traced by the hormones as the primary etchers of his development.

If the heart is enlarged from hypertrophy, if it is the right ventricle that is the most hypertrophied, the apex is not only pushed to the left, but the beat may be rather diffuse, as the enlarged right ventricle will prevent the apex from acting close to the surface of the chest.

Moreover, the hypertrophied follicular cells which constitute the corpus luteum secrete fat which is seen in them in globules.

As long as the heart remains in this hypertrophied condition, which may be called normal hypertrophy since it is needed for the work which has to be done in overcoming the defect in the valve, there are no symptoms, the pulmonary and systemic circulation is sufficient, and the patient does not know that he is incapacitated.

In this case the habits and the stimuli which they involve will be common to both sexes, and the hormones given off by the hypertrophied tissues will act upon the corresponding determinants in the gametocytes.

Brain fag is closely associated with, if not dependent upon, adrenal fag, particularly of the cortex. Brain tissue and adrenal cortex tissue are near relatives, and a normal human brain never develops without a normal adrenal cortex. The adrenal type with an hypertrophied adrenal cortex is always efficient. Among women, the adrenal type is always masculinoid.

In Dickens, the love of lurking, unusual things, human and inanimate he wrote of his discoveries delightedly in his letters was hypertrophied; and it has its part in the simplest and the most fantastic of his humours, especially those that are due to his child-like eyesight; let us read, for example, of the rooks that seemed to attend upon Dr.