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According to this view hyoscyamine ought to be the hyoscinate of hyoscine, or at any rate an isomer of this body. It is to be remarked that they compare hyoscinic acid not with tropic acid, of which it possesses the composition, but with atropic acid, C H O . I have worked with the hyoscyamine of both Merck and Trommsdorff, as well as with a product which I obtained from hyoscyamus seeds myself.
"Oh, no, excuse me, he did not! That's not sold hit or miss. But maybe you mean hyoscyamine. That's another thing." "Why, maybe I do. Look up the sale, can't you, and make sure." "Why should I?" Fibsy explained that in the interests of a police investigation it might be better to acquiesce than to question why, and the young man proved obliging.
These facts prove the presence of atropine in datura; but while Planta and Schmidt assert that only this alkaloid is found in the plant, I have proved that the proportion of atropine in it is but small, while its richness in hyoscyamine is great. I think, therefore, that both Planta and Schmidt must have worked with a mixture of atropine and hyoscyamine.
"Stramonium, all right," he nodded, with satisfaction at the achievement of his night's labours. "That was known as Vitali's test. Yes, there was stramonium in those cigarettes datura stramonium perhaps a trace of hyoscyamine."
I thought it as well, therefore, to recommence the study of daturine, the more so as I had already determined the incorrectness of the long accepted point of fusion of atropine, and that my researches on hyoscyamine convinced me that this base is an isomer of atropine, although very analogous to it. I have also shown that Merck's daturine differs from atropine, and is merely pure hyoscyamine.
A few weeks ago Creake told him that he would not require him again as he was going to do his own gardening in future." "That is something, Louis." "If only Creake was going to poison his wife with hyoscyamine and bury her, instead of blowing her up with a dynamite cartridge and claiming that it came in among the coal." "True, true. Still "
Indeed I verily believe that if all Stowey, Ward excepted, does not go to hell, it will be by the supererogation of Poole's sense of honesty. Charitable! We will have a fair trial of Bang. Do bring down some of the Hyoscyamine pills, and I will give a fair trial of Opium, Henbane, and Nepenthe. By-the-by I always considered Homer's account of the Nepenthe as a Banging lie.
So Terence McGuire learned that Alvord Hendricks bought some hyoscyamine, on a doctor's prescription, about a month ago the same to be used to relieve a serious case of earache. But there was no record of his having bought hyoscyarnus, which was the deadly henbane used in the medicine dropper-nor was there any other record of hyoscyamine against him.
I have succeeded in splitting up "heavy daturine" by two different methods. By recrystallizing the gold salt six times from boiling water, the salt of hyoscyamine, which melts at from 316 deg. F. to 323 deg. F., crystallizes our first, and by the successive evaporation of the mother liquor at last obtain the pure gold salt of atropine, which melts at 275 deg. F. to 280 deg.
Do bring down some of the Hyoscyamine pills, and I will give a fair trial to Opium, Henbane, and Nepenthe. By the bye, I always considered Homer's account of the Nepenthe as a Banging lie." In September, 1803, he gives a gloomy account of his condition. It seems probable that at this time his use of opium must have become habitual: "For five months past my mind has been strangely shut up.
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