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In the pent-in evils which pathology so often shows occurrent in the case of spirit-drinkers, in the vascular, fatty and fibroid degenerations which take place, in the accumulations of rheumatic and scrofulous tendencies, there is the strongest evidence that "and is very prone to initiate serious disturbances amid the normal conduct both of organ and function.

The anatomic changes in the glands and substance of the uterus also favor the irritation, and the development of new growths, which may be malignant or benign as cancers, fibroid growths, and so forth. Hemorrhage at the Menopause a Significant Symptom of Cancer.

If the chronic inflammation is not superimposed on an acute endocarditis there may be no cell infiltration and therefore no softening, but there is a tendency to develop a fibrillated structure, and a fibroid thickening of the endocardium occurs, especially around the valves.

A growth cannot be known as a fibroid tumour without sense testimony, nor its weight estimated without sense testimony, nor a continuous hemorrhage be recorded, or its cessation known without sense testimony, nor can epilepsy be diagnosed, nor bilious attacks recognized without sense testimony.

Here, then, we have indisputable evidence of the fact that the tubercle bacillus may not only enter some of the openings of the body, the nostrils, the mouth, the lungs, but may actually form a lodgment and a growth-colony in the lungs themselves, and yet be completely defeated by the antitoxic powers of the blood and other tissues of the body, prevented from spreading throughout the rest of the lung, most of the invaders destroyed, and the crippled remnants imprisoned for life in the interior of a fibroid or chalky mass.

The local causes may be reflex, as powerful emotions; or due to local disease of the uterus and its appendages, as the various inflammations and displacements of the uterus, fibroid tumors, polypi, and cancer. Dysmenorrhea is painful menstruation.

Such are fibroid changes in the lungs, emphysema, prolonged chronic bronchitis, the last stages of pulmonary tuberculosis, old neglected pleurisies with cirrhosis or fibrosis of the lung, and repeated attacks of asthma anything, whether valvular defect or pulmonary circulatory disturbance, which increases the pressure ahead and the work of this ventricle.

"Concerning the matter of high blood pressure," writes Hare, "independent of cerebral lesions, the longer I study the matter the more convinced I am that this blood pressure is devised by nature to compensate for fibroid changes in peripheral vessels, in order that tissues which would otherwise be cut off from adequate blood supply may receive plenty of blood, and I consider it one of the most vital points to ascertain whether a pressure is what may be called the patient's pathological norm, that is, the pressure which is required in the face of vascular changes, or whether this pressure is in excess of his pathological norm.

"In thirty cases in which alcoholic phthisis was present a dense, fibroid, pigmented change was almost invariably present in some portion of the lung far more frequently than in other cases of phthisis." Annual of Medical Sciences. "There is no form of consumption so fatal as that from alcohol.

Local causes of hemorrhage are: inflammation of the lining membrane of the uterus, chronic pelvic inflammations, faulty uterine positions, erosions and ulcerations of the mouth of the uterus, fibroid tumors, and cancer. All competent observers agree that cancer in women is much commoner from forty to fifty years than at any other age.