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There was double harelip on the left side; the second and third fingers of both hands were webbed for their whole length; the right foot wanted the distal phalanx of the great toe and the left foot was clubbed and drawn inward. The child swallowed when fed from a spoon, appeared to hear, but exhibited no sense of light. It died shortly after the accompanying sketch was made.

However generally distributed arteriosclerosis is, in some regions the disease is more advanced than in others, and in those regions the most serious symptoms will occur. The regions which can stand the disease least well are the brain and coronary arteries, and next perhaps the legs, at the distal parts at least, where the circulation is always at a disadvantage if the patient is up and about.

If we imagine the parent filaria located in a distal lymphatic vessel to abort and give birth to ova instead of embryos, it may be understood that the ova might be unable to pass such narrow passages as the embryo could, and this is really the hypothesis which Manson has put forward on the strength of observations made on two cases.

It is directed downward and backward under the subscapularis and teres major muscles, rounding the posterior part of the humerus, and passing to the anterior and distal end of the humerus, it finally terminates in the anterior carpal region.

Immediate suturing of the ends does not affect the degeneration of the distal segment. The peripheral end undergoes complete degeneration in from six weeks to two months.

The condyles of the humerus articulate with the glenoid cavities of the radius and a portion of the ulna. Two strong collateral ligaments pass from the distal end of the humerus to the head of the radius. The capsular ligament is a large, loose membrane which encloses the articular portion of the humerus with the radius and ulna and also the radioulnar articulation.

The wound was at once opened and blood found oozing from the distal extremities of the carotid artery and jugular vein, which were promptly clamped. The common carotid artery was not sound, so that ligatures were applied to the internal and external carotids and to the internal jugular with a small branch entering into it.

A, Metacarpal bone; B, first phalanx; C, second phalanx, D, third phalanx; E, distal sesamoid bone; 1, volar pouch of capsule of fetlock joint; 2, inter-sesamoidean ligament; 3, 4, proximal end of digital synovial sheath; 5, ring formed by superficial flexor tendon; 6, fibrous tissue underlying ergot; 7, ergot; 8, 9, 9', branches of digital vessels; 10, distal ligament of distal sesamoid bone; 11, suspensory ligament of distal sesamoid bone; 12, 12', proximal and distal ends of bursa podotrochlearis.

The Wallerian doctrine is that the axis cylinders in the central end grow downwards, and enter the nerve sheaths of the distal portion, and continue growing until they reach the peripheral terminations in muscle and skin, and in course of time acquire a myelin sheath; the cells of the neurolemma multiply and form long chains in both ends of the nerve, and are believed to provide for the nourishment and support of the actively lengthening axis cylinders.

Rotation of the distal phalanx necessitates a descent of its apical portion and there occurs a "dropped sole."