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My body is relaxed, my mind is at peace, sleep is coming, I am getting sleepy, I am about to sleep." Never take any sleeping powders except upon the advice of a physician, for the majority of these sleeping powders contain some harmful drug, as morphine, codeine, phenacetin or acetanilid. The latter especially is very depressing to the heart and serves to weaken the nervous system.

The formation of a series of alkaloids under the name of codeines, by the substitution of other organic radicals instead of methyl in the codeine reaction, has already been alluded to. Atropine can be formed by uniting tropine and tropic acid, the two decomposition products already noted.

That's the way she takes it. It produces rhinitis of the nasal passages, which I see you observed, but did not understand. It has a more profound effect than morphine, and is ten times as powerful as codeine. And one of the worst features is that so many people start with it, thinking it is as harmless as it has been advertised.

All the derivatives of opium such as morphine, codeine, heroine, dionine, narceine, and narcotine, to say nothing of bromure d'etyle, bromoform, nitrite d'amyle, and amyline are known to be utilised by the endormeurs to put their victims to sleep, and the skill which they have acquired in the use of these powerful drugs establishes them as one of the most dangerous groups of criminals in existence.

The codeine has the advantage over all other opium preparations that it does not affect the digestive organs, and still acts in a soothing manner. While during last year's sickness my patients lost from ten to twenty pounds of their bodily weight, this year but one lost eight pounds and the other five pounds.

On Tuesday morning, Carol was a mental wreck. She forgot to salt David's eggs, and gave him codeine for his cough instead of tonic tablets for his appetite. She put no soda in the hot cakes, and made his egg-nog of buttermilk.

The face swells, and large blisters form on the cheeks and chin. =Opium.= The inspissated juice of the unripe capsules of the Papaver somniferum. Opium is found in almost all so-called 'soothing syrups' for children, and in Godfrey's cordial, Dalby's carminative, and Collis Browne's chlorodyne. The most important active principles of opium are the alkaloids morphine and codeine.

Its meythl ester, which can be formed from it, is codeine, one of the accompanying alkaloids of opium. Besides the methyl derivative, however, others are possible, and several have been recently prepared, giving rise to a class of artificial alkaloids known as codeines. Morphine, rapidly distilled over zinc dust, yields phenanthren, trimethyl-amine, pyrrol, pyridine, quinoline, and other bases.

They use various derivatives of opium, like morphine and heroin, also codeine, dionin, narcein, ethyl chloride and bromide, nitrite of amyl, amylin, and the skill that they have acquired in the manipulation of these powerful drugs stamps them as the most dangerous coterie of criminals in existence.

If this is poured dropwise into much water, the mixture turns bluish, and if it is then shaken up with ether or chloroform, the form takes a purple and the latter a very permanent blue. Codeine gives the same reaction, but no other of the alkaloids. This reaction can be obtained very distinctly with 0.0004 grm. of morphia. By C. G. SARNSTROM.