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The great progress made in the acclimation of cinchona trees in India, Ceylon, and elsewhere has awakened the governments of countries where the plants are indigenous to the necessity of conserving from reckless destruction, and replanting denuded forests, so as to be able to keep up the supply of this valuable product.

In reply to that I answered that practical medicine would not have existed, had it not known how to treasure up from age to age the facts of popular experience; and I ventured to remark that, had the Countess de Chinchon waited until methodical researches had been made into the physiological action of cinchona bark, before popularizing the remedy, the use of which she had learned from the semi-barbarous Peruvians, in all probability humanity would still, as regards malaria, be dependent upon the medication practiced in the middle ages.

This is the creeping plant that yields the celebrated "sarsaparilla;" and Don Pablo, having made an analysis of some roots, discovered it to be the most valuable species for it is to be remembered, that, like the cinchona, a whole genus, or rather several genera, furnish the article of commerce.

A. O'Leary, Jefferson Medical College, of Philadelphia, says: "The best things in the healing art have been done by those who never had a diploma the first Caesarian section, lithotomy, the use of cinchona, of ether as an anaesthetic, the treatment of the air passages by inhalation, the water cure and medicated baths, electricity as a healing agent, and magnetism, faith cure, mind cure, etc."

The bridge of the Mamabamba conducted the party to a site of the same name, through an interval of forest where might be counted most of the varieties of tree proper to the equatorial highlands. Up to this point the vegetation everywhere abounding had not indicated the presence, or even the vicinage, of the cinchona.

Pepper, coffee, tapioca, cinchona, and ipecacuanha, are being tried successfully; burnt earth, of which the natives have a great opinion, and leaf mould being used in the absence of other manure. The rainfall is supposed to average 100 inches a year, and since thermometrical observations have been taken the mercury has varied from 68 degrees to 92 degrees.

Cinchona also is a work of nature; it is, after all, only the bark of a tree which we might gather for ourselves if we lived in the locality. What a world is this! Though a professed atheist, I delight to bear my testimony to the world. Look at the gratuitous remedies and pleasures that surround our path! The river runs by the garden end, our bath, our fishpond, our natural system of drainage.

For the old abuses of the Company the Government by Parliament has to some extent atoned by fostering the new cultures of tea, coffee, and cinchona, jute and wheat. The system of inducing the ryots to cultivate by advances, protected by a stringent contract law, still exists in the case of opium.

Cinchona also is a work of nature; it is, after all, only the bark of a tree which we might gather for ourselves if we lived in the locality. What a world is this! Though a professed atheist, I delight to bear my testimony to the world. Look at the gratuitous remedies and pleasures that surround our path! The river runs by the garden end, our bath, our fish-pond, our natural system of drainage.

Meconic acid, C H O , which is found in opium in combination with the different bases, has also been investigated. By acting upon meconic acid with ammonia, comenamic acid is formed, and this latter, when heated with zinc dust, yields pyridine. If we go now to the cinchona alkaloids, we meet with exceedingly interesting results.