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Any process that increases the volume of the contents of the vitreous chamber, as hemorrhage, neoplasm, profuse serous or plastic exudation, may by pushing iris and lens forward produce an attack of acute glaucoma. Buphthalmos. Ophth. In all of the cases in which the eye has been examined microscopically obliteration of Schlemm's canal has been reported.
When it does occur it takes place in corneæ that have suffered from keratitis. The alteration is usually in the form of ectasiæ. Often, however, the enlargement of the cornea is irregular. Increase in tension may produce fissures in Descemet's membrane. These occur more frequently in the cornea that have suffered a change in shape, as in buphthalmos.
Fourth: That to glaucoma may be added buphthalmos and staphyloma, as diseases often capable of relief by trephining and indeed toward the relief of which trephining is the best form of operation yet presented. And in occasional cases of blindness of not too long duration, it restores some vision, occasionally to a marked degree.
This may be in the lymph drainage system of the eye; but it may also be in the ocular veins themselves. Experimentally the eyeball can be made to burst by tying all the venous outlets from it. I have seen very high intra-ocular tension develop in a few hours after general thrombosis of the orbital veins. The absence of the canal of Schlemm is noted in congenital buphthalmos.
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