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Apparently morphin and nitrous oxid both act through this interference with oxidation in the brain. We, therefore, conclude that within a certain range of acidity of the blood adrenalin can unite with the brain-cells only through the mediation of oxygen, and that the combination of adrenalin, oxygen, and certain brain-cell constituents causes the electric discharge that produces heat and motion.
One lone light at a window on the top floor suggested that the officer of the night might be awake, but what with the screeching of owls and a wind that sighed among the shrubs, headquarters looked and sounded more like a deserted ancient castle than the cranium and brain-cells of Administration. We heard Yussuf Dakmar stop his cab two hundred yards away.
These adaptive responses to stimuli are the result of the action of the brain-cells, which are thus continually played upon by the stimuli of environment. The energy stored in the brain-cells in turn activates the various organs and parts of the body.
It is, therefore, the purpose of this paper to present the definite results of laboratory researches which show certain relations between alterations in brain functions and physical changes in the brain-cells. Fear. Hyperchromatism was shown only in the presence of the activating stimuli or within a very short time after they had been received.
The phenomena of fear probably are exhibited only by animals whose natural defense is nerve-muscular. The skunk, the porcupine, the turtle, have little or no fear. Fear is born of the innumerable injuries which have been inflicted in the course of evolution. Fear, like trauma, may cause physiologic exhaustion of and morphologic changes in the brain-cells.
Does pain result from physical contact with the nerve-endings, with the physical act of transmitting an impression along the nerve trunk, or with the process within the brain-cells by which energy is released to cause a motor act? It seems most probable that the site of the pain is in the brain-cells. If this be so, then what is the physical process by which the phenomena of pain are produced?
Now, since both psychic and mechanical stimuli cause motor action by the excitation ofprecisely the same mechanism in the brain, and since the more rapid release of energy from psychic stimuli submerges the physical stimuli and prevents pain, it would seem that pain must be a phenomenon which is associated with the process of releasing energy by the brain-cells.
It seemed to grow louder every moment. What was but a murmur on the ear-drum became a roar in the excited brain-cells. Once more were heard the ominous words, "The flood!" They spread from room to room, and from house to house. The wild scenes that had attended the first awakening were tame in comparison with what now occurred. Self-control, reason everything gave way to panic.
Its observed effect upon the brain-cells was that of wide-spread destruction. Infections. For example, in fatal infections resulting from bowel obstruction, in peritonitis, and in osteomyelitis, the real lesion is in the brain-cells.
Practically, any germ of carnal thought will be sure of reception in the protoplasmic brain-cells of a child, who is destined to become a doctor, solicitor, soldier, shopkeeper, labourer, or worker in any ordinary occupation; but the thought-germ that will find entrance to the brain-cells of a future painter, writer, actor, or musician, must represent some propensity of a more or less extraordinary nature.
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