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Are the histologic changes in the liver cells due to metabolism or toxic products, or are they "work" changes incident to the conversion of latent into kinetic energy? Are the brain, adrenals, and liver interdependent? The following facts establish the answers to these queries: The duration of life after excision of the liver is about the same as after adrenalectomy approximately eighteen hours.
Animals upon whom double adrenalectomy has been performed show a striking fall in temperature, muscular weakness, after adrenalectomy the animal may not be able to stand even, and progressive chromatolysis. The Liver. When the function of the liver is impaired by tumors, cirrhosis, or degeneration of the liver itself, then the entire energy of the body is correspondingly diminished.
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