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In the first third of the century, Hugh O'Neil, who succeeded to the lordship of Tyrone in 1198, and died in 1230, was cotemporary with Donnell More O'Donnell, who, succeeding to the lordship of Tyrconnell in 1208, died in 1241, after an equally long and almost equally distinguished career.

The retirement of the archbishop enabled Otto to carry through his business, and withdraw from England on January 7, 1241. On August 21 Gregory IX. died, with his arch-enemy at the gates of Rome and all his plans for the time frustrated. High-minded, able and devout, he wagered the whole fortunes of the papacy on the result of his secular struggle with the emperor.

In this same century Batu, the grandson of Jinghis Khan, came down into Europe with a horde of more than a million Mongols, and tried to repeat the experiment of Attila. Batu penetrated as far as Silesia, and won a great battle at Liegnitz in 1241, but in spite of his victory he had to desist from the task of conquering Europe.

Alexander III. Kings of France. 1180. Philip III. 1223. Louis VIII. 1226. Louis IX. Emperors of Germany. 1209. Friedrich II. 1250. Conrad IV. Popes 1198. Innocent III. 1216. Honorius III. 1227. Gregory IX. 1241. Celestin. Innocent IV. The Fief of Rome! For many years of the reign of Henry III. England could hardly be regarded in any other light.

Adam de Bazinge made, in 1241, by order of Henry III. of England, a cope for the Bishop of Hereford. Cunegonde, Abbess of Goss, in Styria, accomplished numerous important works in that period. Also, Henry III. employed Jean de Sumercote to make jewelled robes of state.

Towards the beginning of the thirteenth century, Chinchiz Khan, leader of a small Tatar tribe, conquered most of Central and Eastern Asia, including China. Under his son, Okkodai, these Mongol Tatars turned from China to the West, conquered Armenia, and one of the Mongol generals, named Batu, ravaged South Russia and Poland, and captured Buda-Pest, 1241.

If the claim of the Castillione ancestry be allowed the archives of the race would be still farther enriched by the name of Pope Celestine IV., Godfrey of Milan, who was elected Pope in 1241, and died the same year. Cardan's immediate ancestors were long-lived.

The shrine was of gold, and, according to Matthew Paris, enriched with jewels. It was commenced in 1241. In 1244 the queen presented an image of the Virgin with a ruby and an emerald. Jewels were purchased from time to time, a great cameo in 1251, and in 1255 many gems of great value. The son of ado the Goldsmith, Edward, was the "king's beloved clerk," and was made "keeper of the shrine."

I published the text of this law, which was issued by the Emperor Frederick II about 1241, in the Journal of the American Medical Association three years ago. It also regulated the practice of pharmacy. Drugs were manufactured under the inspection of the government and there was a heavy penalty for substitution, or for the sale of old inert drugs, or improperly prepared pharmaceutical materials.

Paul's, and at one time physician to Pope Gregory IX, who died in 1241. Toply believes him to have been also the author of the "Anatomia Ricardi," recently published. This Ricardus died in 1252. Now to which of these Ricardi does the eulogistic language of Gilbert refer? Dr. Payne believes it to be the senior, Ricardus Salernitanus. Mr.